Cotylorhynchus was a very large Synapsid that lived in the southern part of what is now North America during the Early Permian period. It was one of the largest terrestrial vertebrates of the Early Permian.

They were herbivores, and because of their enormous size, the adults probably had no predators, not even Dimetrodon could attack. However, the Dimetrodon could devour a juvenile Cotylorhynchus.

Cotylorhynchus was briefly shown in a Chinese prehistoric documentary :

"Back to the Permian 4D"

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